Advancing Pediatric Drug Development

Growth reference of pediatric cancer patients

Briefly describe your research question :

Currently, the pediatric patients growth parameters (e.g., height, weight, BMI, and head circumference) are supposed to be reported relative to the WHO/CDC growth charts.  Since these growth charts represent the growth of healthy children without cancers, it is challenging to understand the impact of the cancer treatment on pediatric patients' growth, especially in interpreting safety data from a single-arm pediatric cancer trial setting.  

Growth curves of pediatric patients with cancers (of any type, overall) would be a helpful reference for understanding, for example, if a certain cancer treatment is helping/delaying children grow like their healthy peers.

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Idea No. 162